Vitelliform macular dystrophy is an inherited eye disorder that can cause progressive vision loss. It causes build-up of fatty yellow pigment (lipofuscin) in the macular area. This, in turn, can damage the light sensitive cells responsible for clear central vision. Sight loss can be variable and can affect central vision in one or both eyes.
There are two main forms of vitelliform macular dystrophy. These are Best vitelliform macular dystrophy (Best disease) and adult-onset vitelliform macular dystrophy, also known as adult-onset foveovitelliform macular dystrophy.
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