Associate Professor Erica Fletcher
Department of Anatomy and Neuroscience, The University of Melbourne
The research will examine how the removal of debris in the eyes changes as we age. This research will be a step towards identifying early markers for those people with a high risk of disease progression. The information gained from this project will be crucial for developing new treatments for macular degeneration.
Associate Professor Fletcher said, “The mechanisms that lead to the early stages of age-related macular degeneration remain to be determined. In this project we will examine a possible cause for the development and progression of early AMD. In particular, we will determine whether signalling of immune cells via receptors called purinergic receptors influences the removal of debris as we age, predisposing people to the disease and also its progression. The information gained from this project will be crucial for developing new treatments targeting immune cell function, as well as using the purinergic receptor as a way of screening those people at greatest risk of disease progression.”
9 October 2013